Abstract
The three new cofactors are 2,4'-bitryptophan-6',7'-dione in methylamine dehydrogenase, 3'-S-cysteinyltyrosine in galactose oxidase and 6-hydroxydopa quinone, or topa quinone in copper-containing amine oxidases. Copper-containing amine oxidases are distinct from other mammalian amine oxidases. From the foregoing, the pharmacological importance of benzylamine oxidase (DAO), diamine oxidase, and plasma amine oxidase is apparent. Antibodies have been extremely useful for immunohistochemical localization of amine oxidases in various tissues of an organism and intracellularly. The reader is directed to two reviews of the literature published prior to 1984 which deal with the localization of copper-containing amine oxidases in mammals. Antibodies against lentil DAO indicate that it is located in all seedling tissues with the highest amounts in the cotyledon. DAO has been obtained from the embryos of Arachis hypogea seedlings. Copper-containing amine oxidases are found in the mycelia when yeast or fungi are grown on monoamines and diamines: Aspergillus niger, Fusarium bulbi-genum, Monascus anka, Penicillium chrysogenum.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.