Abstract
AbstractA copper‐catalyzed direct C−H difluoroacetylation of quinoxalinones at the C‐3 position with ethyl bromodifluoroacetate has been developed. In this reaction, diverse difluoroacetylated quinoxalin‐2(1H)‐ones with a wide range of functional groups could be obtained in moderate to good yields, using cheap, commercially available reagents. This protocol would offer a meaningfully synthetic method for pharmacologically interesting difluoroacetylated quinoxalin‐2(1H)‐one derivatives.magnified image
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