Abstract
Vinyl bromides were subjected to the trifluoroethoxylation reactions with copper reagent [(phen)2Cu][OCH2CF3] at 80°C in DMF with the presence of NaOt-Bu to afford the trifluoroethyl vinyl ethers in good yields. A range of functional groups, such as cyano, nitro, alkoxy, trifluoromethyl, halide, and heterocyclic groups were well tolerated. This approach is also amenable to being performed out on gram scales.
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