Abstract
A copper‐catalyzed annulation of enaminones with maleimides was developed to synthesize various pyrrolo[3,4‐e] isoindoles. In this strategy, 2‐aminopyridine served as a traceless directing group, and target products were obtained in 54‐72% yields. Moreover, a plausible mechanism for this reaction was proposed based on several control experiments, deuterium exchange experiments, and previous reports.
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