Abstract
The paper describes the synthesis and characterization data of new 2-azetidinones containing sulfide groups. Halogenated 2-azetidinones were synthesized by the reaction of ketenes, generated in situ from various carboxylic acid in the presence of Vilsmeier reagent, with different Schiff bases. These compounds on further reaction with several aryl or alkyl halide using copper(I) iodide and sodium thiosulfate produced novel 2-azetidinones including sulfide substituents in N-1 or C-3 or C-4 position. The compounds have been characterized by elemental analysis and spectral (IR, 1H and 13C NMR) data.
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