Abstract
AbstractA copper‐catalyzed oxidative trifluoromethylation of aromatic alkenes has been developed successfully, providing access to a variety of valuable α‐trifluoromethyl‐substituted ketones using Togni's reagent as the trifluoromethyl source. The use of affordable copper catalyst and readily available alkenes as the feedstock, broad substrate scope, mild conditions, and operational simplicity are the attractive features of the method. Preliminary mechanistic studies revealed that both dimethyl sulfoxide (DMSO) and air might function as the oxidant for the transformation.
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