Copper catalyzed N-arylation of sulfonamides with aryl bromides under ligand-free conditions

Abstract

A practical strategy for the C-N cross-coupling of both aliphatic and aromatic sulfonamides with a variety of substituted aryl bromides is reported. Under the optimized conditions, a good representative of N-arylated products were obtained in good to excellent yields (up to 78%) under the ligand-free conditions.