Abstract
Copeptin is a peptide derived from pre-provasospression along with arginine vasospressin. In the setting of aneurysmal subarachnoid hemorrhage (SAH), elevated serum copeptin levels correlate with vasospasm, inpatient mortality, mortality at 1 year, and poor functional outcome at 1 year. The potential role of serum copeptin levels in the management of patients with aneurysmal SAH is promising and should be explored further.
Highlights
Copeptin is a peptide derived from preprovasospression along with arginine vasospressin
Since the larger copeptin is produced in an equimolar ratio with arginine vasospressin (AVP) and is easier to measure in serum, it can be a surrogate marker for AVP
Elevated copeptin levels have been correlated with poor outcomes in ischemic stroke, intraparenchymal hemorrhage, and brain trauma as well as sepsis, pneumonia, and myocardial infarction [6]
Summary
Copeptin is a peptide derived from preprovasospression along with arginine vasospressin. *Correspondence: rtamarg@jhmi.edu Department of Neurosurgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 600 N. The hypothalamic-pituitary axis produces stress hormones such as corticotropin-releasing homone and the nonapeptide arginine vasospressin (AVP).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
