COORDINATION CHEMISTRY OF CYCLOSERINE DERIVATIVES. COMPLEXES OF IRON(II), IRON(III), MANGANESE(II) AND PALLADIUM(II) WITHN4-N'4-TEREFTAL-BIS(CYCLOSERINE)

Abstract

Abstract Synthetic and other studies of iron(II), iron(III), manganese(II) and palladium(II) complexes with the cycloserine derivative, N 4, N ' 4-tereftal-bis(cycloserine) or Terizidone, are reported. The methods used for the characterization of the compounds include elemental analyses, molar conductance, magnetic moments, electronic and infrared spectroscopy and thermal analyses (TG and DTG). From the magnetic properties it was concluded that the above ligand forms low-spin complexes with palladium(II) and high-spin complexes with iron(II), iron(III) and manganese(II). The wavelengths of the principal absorption bands have been accounted for quantitatively in terms of the crystal field theory for manganese(II) and tetrahedral iron(III) complexes. The values of B and C in the iron(III) derivatives are less than in the corresponding manganese(II) complexes. Far-infrared spectra have been extensively studied and the relationship between metal-halogen stretching vibrations and stereochemistry of the complexes is outlined and shown to have potential application in the assignment of the stereochemistry and coordination number of these new metal-halide complexes. The ligand is always monodentate N-bonded through the nitrogen of the imino group of the isoxazole ring. Under our experimental conditions no metal-induced cycloserine ring opening was observed.