Abstract
Together they make a difference: An aryl diazoacetate, H2O, and an α,β-unsaturated 2-acyl imidazole give γ-hydroxyketones with a quaternary carbon stereocenter with excellent selectivity only if all three catalyst components shown in the scheme are present. The Michael addition step did not occur when a similar reagent mixture was treated with the [Rh2(OAc)4] catalyst alone. OTf=triflate, Ts=p-tosyl.
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