Abstract

OBJECTIVE: Airborne and Tuberculosis (TB) control measures have been implemented in Songklanagarind hospital. The infection control unit of the hospital has provided a voluntary two-step tuberculin skin test (TST) for pre-clinical medical students and serial TST for clinical medical students. This study aimed to determine the incidence of negative outcome and booster phenomenon from two-step TST as well as the TST conversion rate from serial TST among medical students in the hospital. MATERIALS AND METHODS: Percentages of negative cases and boosting phenomenon were calculated from the two-step TST records. Conversion rates of each year were calculated from serial TST data. Then the TST conversion rates were predicted based on the Jointpoint model. RESULTS: Two-step TSTs performed from 2001 to 2016 showed 40 to 100% of negative cases and zero to 14% of boosting phenomenon among 2,271 medical students. Serial TSTs from 2002 to 2016 among 665 medical students showed 60 conversion cases. Conversion rates varied from zero to 13.6%. The decline of conversion rates after the year 2006 is demonstrated in 1-Joinpoint model with statistical significance (p = 0.0129). The model corresponded with the timeline data of airborne infection control measures which were mostly implemented after 2006. CONCLUSIONS: A decline in TST conversion rate was shown after 2006. This coincided with airborne infection control measures at the institute. Keywords: tuberculin skin test, conversion rate, medical student, Songklanagarind hospital Address Correspondence to author: Sarinpant Pongpant, MD. Occupational health unit, Department of family medicine and preventive medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand. email: jibpongpant@gmail.com Received: May 25, 2018 Revision received: May 31, 2018 Accepted after revision: July 3, 2018 BKK Med J 2018;14(2): 17-21. DOI: 10.31524/bkkmedj.2018.09.004

Highlights

  • Systemic testing and treatment for latent tuberculous infection (LTBI) should be considered in health care workers at risk.[5] Medical students are at risk for TB infection during their clinical years.[6,7,8,9,10] TB control in healthcare settings plays an important role in limiting transmission from patient-to-patient, patient-to-healthcare worker and healthcare worker–to-patient.[1,11] Tuberculin skin test (TST) is a classic, widely-used and affordable screening tool for LTBI.[12,13] Casas et al found that annual TST conversion in healthcare workers (HCW) has declined during the 20-year period of their study

  • This study aimed to evaluate trends in serial TST survival from 2001-2016 with TB control implementation

  • Exclusion criteria: Records without data from the serial tuberculin skin test were not included in the calculation of TST conversion rate

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Summary

Introduction

Systemic testing and treatment for LTBI should be considered in health care workers at risk.[5] Medical students are at risk for TB infection during their clinical years.[6,7,8,9,10] TB control in healthcare settings plays an important role in limiting transmission from patient-to-patient, patient-to-healthcare worker and healthcare worker–to-patient.[1,11] Tuberculin skin test (TST) is a classic, widely-used and affordable screening tool for LTBI.[12,13] Casas et al found that annual TST conversion in HCW has declined during the 20-year period of their study. The tool should include local epidemiological, climatic and socioeconomic status alongside TB and HIV burden.[1] Songklanagarind hospital has provided an annual voluntary TST for medical students before and during their clinical year. Records of TST results from the infection control unit were used.

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