Abstract

1. 1. Activities evoked in the Centrum Medianum (CM) by applying isolated electric shocks to homo- and contralateral cortices were picked up with macroelectrodes. The lowest threshold response is elicited by stimulating the motor, S II and inferior temporal areas (4 V vs 7 V for the suprasylvian region). Zona incerta and the suprasylvian cortical sites onto which the CM-relayed ascending impulses project are also activated. 2. 2. Impulses generated by peripheral and cortical stimulations mutually occlude within CM and suprasylvian cortex. 3. 3. A microphysiological study of units in CM has been carried out (animals under chloralose and awake curarized ones). Convergences of impulses from various peripheral and cortical origins could be observed on single units in the two kinds of preparations. 4. 4. The different kinds of interactions between these converging impulses suggest that the long-lasting depressions are not due to true refractory periods but to a phase of inhibition. 5. 5. The following points have been discussed: Existence and modalities of the phase of inhibition, localisation of the interactions, homology of the cortical regions that project towards the CM, the Caudate nucleus and the mesencephalic Reticular Formation.

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