Abstract
The aim of this study was to screen the suspected cervical cancer patients (n=100) by liquid-based cytology and conventional pap’s smear followed by colposcopic biopsy from July 2016 to June 2017. In conventional pap’s test, 73 cases were true negative whereas 25 cases were false negative. However, in liquid-based cytology, 68 cases were true negative and 23 cases were false negative. Finally when colposcopic examinations were done, 61 cases were true negative and 15 cases were false negative. The sensitivity of liquid-based cytology was 11.5% for cervical cancer screening which was more than the conventional pap’s smear (3.8%). In conclusion, liquid-based cytology should be more preferable method than the than conventional pap’s smear for the diagnosis of precancerous lesion of the cervix.
Highlights
Cervical cancer is the second most common causes of death in gynecological cancer of women.[1]
Regarding the report of cervical cancer screening tests, conventional pap’s test, liquid based cytology, colposcopic guided biopsy were done from 100 patients (Table I)
The results of the conventional cytology was negative for CIN (98%) and ASCUS (2%)
Summary
Cervical cancer is the second most common causes of death in gynecological cancer of women.[1] For the last 60 years, the mainstay of cervical cancer screening is Papanicolaou test (pap test). It involves the examination of exfoliating cells from the transformation zone and detects cancerous or precancerous lesion. The test can be performed by traditional method or liquid-based cytology. In liquidbased cytology, collected cells are released into a vial of liquid preservative that is used for microscopic evaluation of the cells. Traditional pap test involves direct transfer of the cervical cells to a microscope slide for evaluation. When abnormal cells are detected on the pap test, colposcopy is indicated.[2]
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