Conventional Echocardiography changes in Children with Diabetes Mellitus Type I with Lipid Profiles the Variation

Abstract

Introduction: Diabetes mellitus type I (DMTI) is a highlighted endocrine and digestion issue that involved heart organs with more effect when lipid profiles considered. The study aimed to assess the conventional echocardiographic changes in children with diabetes mellitus type I with their lipid profiles variation. Materials and Methods: This analytical and comparison study performed on 96 DMTI and 96 healthy children. The examination run with collaboration of endocrinology and cardiology between March 2018 and April 2019. The DMTI confirmed by the clinical manifestation and laboratory measures. Both groups underwent conventional echocardiography and HbA1c, diabetic duration and lipid profiles measured for the children with diabetes. Data analyzed via SPSS 18.0 and P < 0.05 was considered significant level. Results: About 52.6% and 47.9% were boys in participants and patients respectively. Mean age of participants was 10.82± 3.15 years and 10.87±3.46 and 10.77±2.82 years for patients and controls respectively. Left MPI was higher in patients (p=0.001). Patients with poor controlled had higher LVMI and left DT (p<0.05). Patients with abnormal CHO had higher EF, FS, left E/A, LAd/Aod, LAs/Aos, left ET and PWD when right DT, aortic diameter in diastole, aortic diameter in systole, left MPI and left DT had lower levels. LDL effects on aorta diameter in diastole, right deceleration time, aorta diameter in systole, left MPI and left DT, FS, Left E/A, LAd / Aod, LAs/Aos, and PWD. Patients with abnormal HDL, had higher left MPI and lower left ET. Conclusion: It was concluded that more conventional echocardiography involvement in DMTI children who have abnormal lipids profile as well as abnormal HbA1c and longer diabetes duration.