Abstract

The treatment of rectal cancer is evolving at a rapid pace in parallel with advancements in surgical technique. One such advancement is the application of the laparoscopic platform to the transanal approach, coined transanal minimally invasive surgery (TAMIS). TAMIS overcomes many of the shortcomings of the traditional transanal approach to the local resection of rectal neoplasia, offering greater visualization and access to the middle and upper rectum with improved oncologic outcomes. Following the introduction of conventional TAMIS, the robotic platform was introduced and applied in analogous fashion. Over the past decade, data have accumulated enabling the comparison of the two approaches most notably with regard to patient morbidity, mortality, and oncologic outcomes. This review discusses the most recently available outcomes regarding conventional and robotic TAMIS and provides a comparison of the two platforms in the treatment of rectal neoplasia. While randomized controlled trials comparing the two platforms are lacking, important differences have been identified. Conventional TAMIS is the more cost-effective approach while advancements in the robotic platform allow the surgeon to be seated and ergonomically optimized, allowing greater visualization and ease of suturing. Differences in oncologic outcomes between the two platforms have not been identified. Head-to-head randomized controlled trials are required to determine if any differences in functional or oncologic outcomes exist.

Highlights

  • Our understanding of rectal cancer is advancing at a rapid pace

  • Albert and Larach were the first to report this application in their seminal paper describing the approach of singleport laparoscopy, coining the term transanal minimally invasive surgery (TAMIS) in 2009[1]

  • TAMIS was established to serve as an alternative to transanal endoscopic microsurgery (TEM)

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Summary

Introduction

Our understanding of rectal cancer is advancing at a rapid pace. Treatment options have expanded requiring surgeons to be facile at traditional open surgery, and minimally invasive techniques, such as the laparoscopic and robotic platforms. Mean follow-up for patients with benign and malignant lesions undergoing TAMIS for curative intent was 13.6 ± 17.3 months and 14.4 ± 17.4 months, respectively, with local recurrence rates of 3 and 6%, with distant metastases in 2%. Mean time to recurrence following resection of both benign and malignant lesions was 17 months. Cumulative diseasefree survival for patients undergoing resection of benign neoplasms was 98, 94, and 94% and for malignant neoplasms 96, 93, and 84% at 1-, 2-, and 3-year follow-up, respectively.

Results
Conclusion

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