Abstract
Since its introduction by Weissbecker1in 1897, scarlet fever convalescent serum has proved useful in the treatment of scarlet fever. The results obtained have been variable, probably because there has been much variation in the size of the doses used. Among sixteen authors2reporting results since 1912, the therapeutic dose varied from 10 to 240 cc. At present the trend is toward smaller doses. Reports of protection of contacts by means of convalescent serum are meager. Degkwitz3treated 509 scarlet fever contacts, using 5 or 6 cc. for children up to 8 years of age and 10 cc. for those from 9 to 14 years of age. All but three escaped the disease. Neff4used convalescent serum in doses of from 15 to 30 cc. for prophylaxis in twenty-five contacts, with no failures. Meader5of the Detroit health department reports that, of 450 contacts who
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