Abstract
The guiding principle of plasma therapy can be utilized for prophylaxis and treatment reasons, taking into account non-availability of suitable vaccination for prevention or no settled conclusive cure for SARS-CoV-2, plasma therapy is obtaining importance in a current pandemic as one of the treatment options of COVID-19. Despite the fact that, it has been said to be a useful approach in exceptional preliminary studies, convalescent plasma (CP) treatment has various limitations. In this review, an attempt has been made to audit positive viewpoints, negative views and specific limitations of the CP therapy for COVID-19 cases. The outcomes of various studies show that CP treatment would possibly be considered one of the alternatives but while questioning about it as a therapeutic approach, thinking about beneficial aspects, the negative aspects and barriers are to be considered before its administration as a therapeutic agent.
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