Abstract
SummaryIt has been shown that elevated level of IL10 with an IL10/IL6 ratio greater than 1 is very evocative of Primary Vitreo Retinal Lymphoma (PVRL). However, other causes of uveitis can be accompanied with increased IL10 level, and on the other hand some pateints with PVRL may be characterized by normal levels of intraocular IL10 ((intraocular T‐cell lymphoma or subretinal lymphoma without vitreous infiltration). Currently, the decision to treat the patients cannot be based on the sole basis of increased IL10 level in aqueous humor. Systemic chemotherapy or radiation therapy can be associated with severe side effects, especially in elderly patients. In patients with a negative cytological analysis of the vietrous, the role of increased intraocular cytokines in the aqueous humor for the therapeutic decision is very debated and is currently not sufficient in order to confirm the diagnostic. However, the role of intraocular cytokine dosage in the aqueous humor to follow‐patients during and after treatment has to be discussed.
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