Abstract
Non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) is a heterogeneous group of mesenchymal tumours distinct from rhabdomyosarcoma that affects children and adolescents, with clinical presentation varying from relatively benign to highly malignant.1,2 To develop a consensus approach to NRSTS, the International Soft-Tissue Sarcoma Consortium (INSTRuCT)3 was founded by the leadership of three large cooperative groups—the Children's Oncology Group (COG), the Cooperative Weichteilsarkom Studiengruppe (CWS), and the European paediatric Soft tissue sarcoma Study Group (EpSSG)—to pool expertise and resources to improve knowledge of these tumours in children, adolescents, and young adults, and to improve patient outcomes.
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