Controlled Synthesis of Hyperbranched Poly (ester)s From Biorenewable Monomers for the Delivery of Therapeutic Agents

Abstract

A series of hyperbranched poly(ester)s (HBPEs) has been prepared from renewable bio monomers using the Macosko-Miller conditional probability model (appropriate for monomers containing functional groups of unequal reactivity) to select ratios of reactants (ratios of reactive functional groups) to permit high monomer conversion without gelation and to assure the presence of specific reactive end groups.