Abstract
Malvidin belongs to the class of anthocyanidin, a pigment compound present in fruits and vegetables like the colored berries, flowers, and vegetables which have pigments on it and it is available commercially as malvidin chloride. Malvidin is known to possess many medicinal characteristics like anti-microbial, anti-diabetic, anti-inflammatory, anti-obesity, and anti-cancer. In this research paper, a 3D printing technique is used which evolves a 3D printer based on desktop that extrudes tablets comprising the active drug which here is malvidin our main ingredient and the other excipients which are used as binders and disintegrants. Methods which are adapted here for the formulation of 3D printed tablet make the tablets appropriate for immediate and sustained release with its definite physical and mechanical properties like hardness, friability, and weight. Tablets that are extruded by the 3D printer are controlled release bi-layer tablets. Due to involvement of 3D printer, printing cost for the bi-layered tablets found very low that makes our method as cost efficient.
Highlights
1.1 Solubility of MalvidinMalvidin is an anthocyanidin which can be obtained from pigmented fruits, vegetables and flowers
In our research we found that anthocyanins are soluble in water but for the exception, malvidin is soluble slightly in water
Intended for immediate release layer: The malvidin powder along with required excipients intended for immediate release layer that have been utilized here are microcrystalline cellulose (MCC) and sodium carboxymethyl cellulose (SSC) that were mixed for minimum 30 minutes of time interval
Summary
Malvidin is an anthocyanidin which can be obtained from pigmented fruits, vegetables and flowers. Anthocyanidin is a natural pigment which is the precursor anthocyanins which gives us the blue-red colours of fruits and flowers [1]. Malvidin is plant pigment and is biologically active. Cell signaling can be studied as an inhibitor of 3′, 5′cyclic adenosine monophosphate (cAMP) phosphodiesterases (PDE) and some cGMPspecific phosphodiesterases of o-methylated anthocyanidin. Malvidin can be used as reference material for anthocyanidin glycosides.
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