Abstract
The ineffectiveness of current strategies for chemical control of mosquito vectors raises the need for developing novel approaches. Thus, we carried out a literature review of strategies for genetic control of mosquito populations based on the sterile insect technique. One of these strategies consists of releasing radiation-sterilized males into the population; another, of integrating a dominant lethal gene under the control of a specific promoter into immature females. Advantages of these approaches over other biological and chemical control strategies include: highly species-specific, environmentally safety, low production cost, and high efficacy. The use of this genetic modification technique will constitute an important tool for integrated vector management.
Highlights
We carried out a literature review in order to collect information on alternative forms of vector control, focusing on mosquitoes of the Anopheles and Aedes genera
In the last century, during the 1950’s and 60’s, vector control programs in many countries were based on chemical strategies that made unrestricted use of insecticides such as DDT
These measures led to the successful eradication malaria from Southeastern Europe and Taiwan, and reduced the morbidity rate in India from roughly 75 million to about 100 thousand cases per year.[7]
Summary
We carried out a literature review in order to collect information on alternative forms of vector control, focusing on mosquitoes of the Anopheles and Aedes genera. In the last century, during the 1950’s and 60’s, vector control programs in many countries were based on chemical strategies that made unrestricted use of insecticides such as DDT. These measures led to the successful eradication malaria from Southeastern Europe and Taiwan, and reduced the morbidity rate in India from roughly 75 million to about 100 thousand cases per year.[7] Prior to this effort, pyrethroid-based insecticides were intensely used in the 1930’s to fight Anopheles gambiae, leading to the eradication of this species from Northeastern Brazil. The aim of the present study was to revisit strategies of genetic control of mosquito vector populations
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
