Abstract
A recently published report suggests that, in human breast cancer cells, the expression of vascular endothelial cell growth factor (VEGF) (one of the most potent angiogenesis factors currently known) is stimulated by the presence of progestins. Salman M. Hyder et al. (University of Texas Health Science Center, Houston, TX, USA), writing in the International Journal of Cancer (15th May), suggest that anti-progestins might play a role in preventing tumor progression in patients with breast cancer.
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