Abstract
Abstract After infection, the ten double-stranded RNA genome segments of bluetongue virus are transcribed into ten single-stranded mRNA species. The relative molar proportion of these mRNA species were determined by means of hybridization ex-experiments. Specific regulation at the level of transcription is indicated. The similarity in molar ratios for in vitro and in vivo synthesized mRNA indicates that this control is a property of the virus particle itself. The relative frequency of transcription of the respective genome segments remains unaltered during the course of infection. By isolating bluetongue virus single-stranded RNA from polyribosome complexes in the cell, it is also shown that the relative molar ratio in which the mRNA species become attached to the ribosomes is similar to the ratio in which they are synthesized.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
