Abstract
Modification of micellar phases with solubilized solutes was examined to control the separation in micellar electrokinetic chromatography (MEKC). The addition of organic hydroxy compounds (1-hexanol, cyclohexanol and phenol) as modifiers to a micellar solution of sodium dodecyl sulfate specifically decreased the capacity factor of some aromatic analytes possessing hydrophilic functional groups. The effect of phenol was different in selectivity to that of 1-hexanol and cyclohexanol. The effects of these modifiers were mainly explained in terms of the saturation of the micellar palisade layer with the modifiers and the hydrogen-bond interaction between the modifier and analyte molecules in the micellar phase. Such micellar modification were applied to improve the MEKC separation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
