Control of regioselectivity in the Diels–Alder reactions of alkyl-substituted 1,4-benzoquinones by β-cyclodextrin and its derivatives

Abstract

The Diels-Alder reactions of benzoquinones 1-3with penta-1, 3-diene 4 and isoprene 5 are studied in aqueous cyclodextrin solutions, where highly enhanced ortho(6, 8 and 10) and meta(13, 15) regioselectivities are achieved.