Control of reaction pathways in the photochemical reaction of a quinone with tetramethylethylene by metal binding.

Abstract

The present study reports a novel supramolecular photochemical reaction that focuses on the direct electronic interactions between a host reaction substrate and guest metal salts. The reaction pathways in the photochemical reactions of quinone derivatives bearing a methoxy group and a long oligoether sidearm QEn (n = 0 and 3) with tetramethylethylene (TME) are changed upon noncovalent complexations of the host reactant with alkali and alkaline earth metal ions and a transition metal salt. The photochemical reaction of QEn with TME provides a mixture of [2 + 2] cycloadducts 1aEn and 1bEn, hydroquinone H2QEn, and monoallyl ether adducts of hydroquinones 2aEn and 2bEn. The photochemical reaction proceeds by the photoinduced electron transfer mechanism, where photoirradiation brings about formation of a radical ion pair [QEn˙(-), TME˙(+)] as the primary intermediate. We found that the yields and selectivity of these photoproducts are changed upon electronic interactions of QEn˙(-) with the metal salts. The photochemical reaction in the absence of metal salts provides H2QEn as its major product, whereas QE3, having the long sidearm, dominantly produces 2aE3 at the expense of 1aE3, 1bE3, and H2QE3 when it forms a size-favorable host-guest complex with divalent Ca(2+). In contrast, QEn selectively provides oxetanes 1aEn and 1bEn in the presence of Pd(OAc)2, which can form complexes with the quinone through metal-olefin and coordination interactions in the ground and photoexcited states of the quinone.