Control of contamination of raw milk by antibiotics

Abstract

Foreign biologically active substances that can be contained in milk of cows, which having a negative impact on the health and quality of life of people are antibiotics. Intensive use of antibiotics in veterinary practice contributes to the globalization of micro doses in the environment, accelerates the evolution and spread of resistant forms of microorganisms. The principle of prioritizing the safety of dairy products, based on the mandatory control of raw milk for the content of residual amounts of antibiotics, is implemented in accordance with the requirements of regulatory and technical documents. There is a need to use high-tech laboratory methods of detection of antimicrobial drugs in raw materials and livestock products. The purpose of the research was to control the contamination of raw milk by antibiotics. Raw milk of morning milking from cows of Black-and-White breed was used for the research. Milk was obtained at the zoo station of the Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”. In the samples residual amounts of antibiotics of diff erent pharmacological groups, most widely used in productive animal husbandry were determined. Sampling of raw milk and their preparation for research was carried out in accordance with State Standard T 26809.1-2014. The determination of residual amounts of antibiotics was carried out by the method of an internal standard for the areas of chromatographic peaks of identifi ed compounds using a calibration characteristic obtained by analyzing calibration solutions of known compounds under similar conditions. It was established that monitoring the health of lactating cows, strict compliance with the rules for the use of veterinary medicines, the exclusion of errors in the technology of production of feed and feed additives, contribute to minimizing contamination of raw milk by antibiotics.