Abstract
Non-smoking products for oral consumption are a growing segment of the nicotinecontaining products market and, therefore, the study of the component composition and toxicological load during its consumption is an urgent task. The toxic components of nicotine-containing products are the subject of research in scientific laboratories and are carried out by various methods. Studies have been monitored for potential toxicity determinations of tobacco and non-tobacco smokeless products. The article presents the results of monitoring methods for determining toxic components that determine the risk of nonsmoking products, carried out at the Federal State Budgetary Scientific Institution ARSRCTTP. As a result of the research, methods for the quantitative determination of nicotine content have been determined and the method for the determination of tobacco-specific nitrosamines (TSNA) using high-performance liquid chromatography in the product under study has been validated.
Highlights
Федеральное государственное бюджетное научное учреждение «Всероссийский научноисследовательский институт табака, махорки и табачных изделий»; ул
The toxic components of nicotine-containing products are the subject of research in scientific laboratories and are carried out by various methods
Studies have been monitored for potential toxicity determinations of tobacco and non-tobacco smokeless products
Summary
Федеральное государственное бюджетное научное учреждение «Всероссийский научноисследовательский институт табака, махорки и табачных изделий»; ул. Некурительная продукция орального потребления – растущий сегмент рынка никотинсодержащей продукции, и следовательно, изучение компонентного состава и токсикологической нагрузки при ее потреблении является актуальной задачей. Потенциально применимых для определения токсической нагрузки табачной и нетабачной некурительной продукции. В результате исследований определены методы количественного определения содержания никотина и валидирована методика определения табакоспецифичных нитрозаминов (ТSNА) с помощью высокоэффективной жидкостной хроматографии в исследуемой продукции.
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