Abstract
The application of an imidazole derivative (KK-42), body ligation and extirpation of specific ganglia suggest a new endocrine mechanism responsible for the regulation of diapause in pharate first-instar larvae of insects. The present results indicate that a humoral repressive factor originates in the region of the mesothorax and that a humoral maturation factor is released from the region of the 2nd to 5th abdominal segments. Our data suggest that the former inhibits the action of the latter during diapause.
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