Abstract
During the first few years of the twenty first century, the complex mechanisms which characterise the control of bone remodelling were just beginning to be recognised and starting to be investigated. Results of the overwhelming amount of research subsequently published have illuminated the extreme complexity of the cellular and molecular interactions as well as the network of interwoven highways and byways representing the numerous pathways that transport factors to stimulate or to inhibit specific cellular activities. A highly significant aspect of the results of these investigations is the unequivocal demonstration of the participation of many of these pathways not only in the control of bone remodelling but also in numerous processes – both physiological and pathological – involving other organs and tissues and as such are examples of systems biology.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
