Contribution to the Study of The Antipyretic Effects of Aqueous Extracts of Two Plants « Urtica dioica and Nerium oleander ».

Abstract

The current treatment of febrile conditions involves non-steroidal anti-inflammatory drugs (NSAIDs), which are widely prescribed because of their efficacy in the management of pain, fever, and inflammation. However, their long-term therapeutic use is often associated with adverse effects such as gastrointestinal ulcers. Therefore, current research is based on the substitution of chemical treatments with natural treatments that are equally effective but have fewer side effects. One of the most widespread remedies is the use of substances of plant origin. Urtica dioica and Nerium oleander are two medicinal plants widely used for the treatment of various diseases in traditional medicine. The aim of this study was to evaluate the antipyretic effect of the aqueous extract of these plants in vivo. The administration of these extracts significantly reduced brewer's yeast-induced hyperthermia. The results of this study contribute to validating the medicinal virtues of these plants, especially in the treatment of febrile states. The phytochemical constituents are probably responsible for their pharmacological properties and could replace some drugs as they cause undesirable side effects.