Contribution of the anterior insula to temporal auditory processing deficits in adolescents and adults with developmental dyslexia

Abstract

Event Abstract Back to Event Contribution of the anterior insula to temporal auditory processing deficits in adolescents and adults with developmental dyslexia Claudia Steinbrink1*, Hermann Ackermann2, Thomas Lachmann1 and Axel Riecker3 1 University of Kaiserslautern, Department of Psychology II, Germany 2 University of Tuebingen, Department of General Neurology, Hertie Institute for Clinical Brain Research, Germany 3 University of Ulm, Department of Neurology, Germany Developmental dyslexia may result from general deficits concerning rapid temporal integration of acoustic stimuli. Assuming that the effort of auditory temporal processing of speech and non-speech stimuli increases with presentation rate, fMRI measurements were performed in dyslexics and controls during passive listening to series of syllables and click sounds using a parametric approach. Controls showed a decrease in hemodynamic brain activation in the right and an increase in the left anterior insula as a function of increasing presentation rate of click as well as syllable trains. By contrast, dyslexics exhibited this profile of hemodynamic activation in the click condition only. As concerns syllables, activation in dyslexics did not depend on presentation rate. Moreover, a subtraction analysis of hemodynamic main effects across conditions and groups revealed decreased activation of the left and right anterior insula in dyslexics as compared to controls in both the click and the syllable condition. These results indicate, in line with preceding studies, that in healthy adults the insular cortices are involved in auditory temporal processing of non-linguistic stimuli. Furthermore, they demonstrate that these operations of the intrasylvian cortex extend to the linguistic domain. Crucially, our data suggest that the anterior insula represents an important neural correlate of deficient temporal processing of speech and non-speech sounds in dyslexia. Conference: EARLI SIG22 - Neuroscience and Education, Zurich, Switzerland, 3 Jun - 5 Jun, 2010. Presentation Type: Poster Presentation Topic: Language and reading Citation: Steinbrink C, Ackermann H, Lachmann T and Riecker A (2010). Contribution of the anterior insula to temporal auditory processing deficits in adolescents and adults with developmental dyslexia. Front. Neurosci. Conference Abstract: EARLI SIG22 - Neuroscience and Education. doi: 10.3389/conf.fnins.2010.11.00029 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 31 May 2010; Published Online: 31 May 2010. * Correspondence: Claudia Steinbrink, University of Kaiserslautern, Department of Psychology II, Kaiserslautern, Germany, steinbrink@sowi.uni-kl.de Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Claudia Steinbrink Hermann Ackermann Thomas Lachmann Axel Riecker Google Claudia Steinbrink Hermann Ackermann Thomas Lachmann Axel Riecker Google Scholar Claudia Steinbrink Hermann Ackermann Thomas Lachmann Axel Riecker PubMed Claudia Steinbrink Hermann Ackermann Thomas Lachmann Axel Riecker Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.