Abstract
SummarySmall intestine DNA and net small intestine transport of sodium were measured in bile-duct-ligated and sham-operated rats. DNA analyses indicated that bile played no measurable role in the extent or rate of loss, or rate of repair of the mucosa after x-irradiation. Net transport of sodium was measured in vivo after 1500 R x-irradiation in animals with and without bile-duct ligation. Three days after irradiation, leakage of sodium across the intestine from blood to lumen occurred in the absence of bile and bile acids had no significant effect on the magnitude of the leakage. It is concluded that the major contribution of bile to small intestine sodium loss after irradiation is the secretion of bile sodium rather than an action of bile acids on the intestinal transport process.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International journal of radiation biology and related studies in physics, chemistry, and medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
