Abstract

Activity and crowding effect is crucial in conformational change and relevant dynamics of biomolecules in complex environment, which remains a challenging problem. We perform a systematic Langevin simulation to investigate the conformational properties of a flexible polymer in an active bath. Firstly, we modulate both active force and bath particle size to probe the activity-induced polymer swelling. Results indicate a significant crowder size effect. Moreover, polymer conformational change shows a monotonic scaling on dynamical persistence length of active particles. Secondly, activity-crowding competition effect is rationalized. An intriguing shrinkage-expansion crossover of polymer dimension is observed with increasing activity.

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