Abstract
Contrast-enhanced ultrasound (CEUS) is a relatively new addition to the diagnostic armamentarium in the United States. The pairing of intravenously injected contrast agents with advanced ultrasound image processing techniques permits improved detection and characterization of different tissue types compared with conventional sonography. The use and efficacy of CEUS is well established in echocardiographic applications in the United States and in many other applications worldwide. Recent approval by the U.S. Food and Drug Administration of an ultrasound contrast agent for use in evaluating adult and pediatric hepatic pathology opens the door to a new era in sonographic diagnosis. An understanding of the underlying physical and technical principles of CEUS is essential for the accurate interpretation of the information obtained from this exciting emerging modality.
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