Abstract
Continuous propofol and bolus propofol result in similar sedative use during endoscopic retrograde cholangiopancreatography: A retrospective study
Highlights
Endoscopic retrograde cholangiopancreatography (ERCP) is an important procedure to diagnose and treat biliary and pancreatic diseases
An initial dose of 2.5 mg midazolam was applied to all patients to induce deep sedation, in addition to an initial dose of propofol that depended on body weight, blood pressure, and oxygen saturation
Total propofol dose was significantly correlated with procedure duration (r=0.685; p
Summary
Endoscopic retrograde cholangiopancreatography (ERCP) is an important procedure to diagnose and treat biliary and pancreatic diseases. Both the diagnosis and the intervention can be performed during a single session. A disadvantage of midazolam is its short elimination half-life. It is not recommended that benzodiazepines be used alone for sedation during complex and/or long endoscopic procedures. Propofol is a short-acting, intravenously administrated hypnotic agent that is often used in endoscopic sedation. Propofol can cause deep sedation or abrupt respiratory failure. Despite these disadvantages, propofol has been proven safe for sedation during endoscopic procedures [8]. Endoscopic retrograde cholangiopancreatography is a complex, lengthy, and uncomfortable procedure. A combination of midazolam and propofol is used, with propofol being administered as a continuous infusion or an intermittent bolus
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