Continuous Insulin infusion therapy for acute stress hyperglycaemia secondary to asthma exacerbation in a paediatric emergency setting

Harsha Hanumanthaiah,Sze May Ng,Arundoss Gangadharan

doi:10.7243/2050-0866-1-19

Harsha Hanumanthaiah, Sze May Ng + Show 1 more

Open Access

https://doi.org/10.7243/2050-0866-1-19

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Abstract

Introduction Hyperglycaemia is thought to be an adaptive response to stress and is recognized to be associated with an adverse outcome. Although mild stress hyperglycaemia in paediatric illness is common, severe hyperglycaemic responses (≥25 mmol/L) to stress are unusual in children. The role of intravenous insulin infusion therapy in the treatment

Highlights

Hyperglycaemia is thought to be an adaptive response to stress and is recognized to be associated with an adverse outcome
We recommend that intravenous insulin therapy may be used for initial treatment of severe stress hyperglycaemia in children presenting acutely unwell in an emergency setting
We report a case of acute severe stress hyperglycaemia in 5 year old girl without pre-existing diabetes presenting with severe asthma exacerbation in an emergency setting

Summary

Introduction

Hyperglycaemia is thought to be an adaptive response to stress and is recognized to be associated with an adverse outcome. Conclusion: We recommend that intravenous insulin therapy may be used for initial treatment of severe stress hyperglycaemia in children presenting acutely unwell in an emergency setting. Mild stress hyperglycaemia in paediatric illness is common, severe hyperglycaemic responses (≥25 mmol/L) to stress are unusual in children.

Results

Conclusion