Abstract

We had reported advantage of continuous hyperthermic peritoneal perfusion (CHPP) for the prevention of peritoneal recurrence after surgery for gastric cancer in a historical control study. We performed CHPP (CHPP group, n=22) or continuous normothermic peritoneal perfusion (CNPP group, n=18) combined with cisplatin and mitomycin C for the prevention of peritoneal recurrence. The survival curve of the CHPP group was significantly better than of the CNPP group in log-rank test (p<0.01). This fact showed that not only intraperitoneal perfusion combined with chemotherapy (CNPP) but also intraperitoneal hyperthermia(CHPP) are effective procedures for prevention of peritoneal recurrence.

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