Abstract
AbstractThe first continuous flow syntheses of amido and thiolato families are reported. Our studies focused on [M(NHC)(Cbz)] (Cbz=carbazolyl) and [M(NHC)(SPh)] (NHC=N‐heterocyclic carbene) as general proof‐of‐concepts and has led to a simple protocol with unprecedented short reaction times and high product yields. The scope of supporting ligands and substrates permits to assess the versatility of the process and a one‐pot synthesis starting from the imidazolium salt, metal source and carbazole substrate highlights the simplicity and sustainability of this operating design. The process was made possible through a detailed mechanistic understanding of the underlying reaction chemistry.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
