Abstract
Pain after liver resection can be difficult to manage. Epidural anesthesia (EA) isaneffective technique inpain control inthis surgery.
 However, postoperative coagulopathy and hypotension due to autonomic nervous system block in high-risk patients, may result that the EA is an inadequate analgesic technique in according to enhanced recovery after surgery (ERAS) recommendations for liver surgery.
 Regional block techniques have been recommended for liver surgery in ERAS guidelines.
 Erector spinae plane (ESP) block is a recent block described for thoracic and abdominal surgeries and provides both somatic and visceral analgesia.
 We describe a high-risk patient with cardiac dysfunction and Parkinson’s disease who underwent laparoscopic right liver resection for hepatocellular carcinoma.
 Satisfactory intra and postoperative analgesia was achieved by a combined continuous ESP block, transversus abdominis plane (TAP), and oblique subcostal TAP blocks.
 Surgery and postoperative period was uneventful. No opioids were administered during hospitalization.
 A combined of thoracic and abdominal wall blocks can be an effective approach for intra and postoperative analgesia in highrisk patients undergoing laparoscopic liver resection.
 Further clinical research is recommended to establish the effectiveness of the ESP block as an analgesic technique in this surgery.
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