Abstract

BackgroundIndia has the largest number of under-five deaths globally, and large variations in under-five mortality persist between states and districts. Relationships between under-five mortality and numerous socioeconomic, development and environmental health factors have been explored at the national and state levels, but the possible spatial heterogeneity in these relationships has seldom been investigated at the district level. This study seeks to unravel local variation in key determinants of under-five mortality based on the 1991 and 2011 censuses.MethodsUsing geocoded district-level data from the last two census rounds (1991 and 2011) and ordinary least squares and geographically weighted regressions, we identify district-specific relationships between under-five mortality rate and a series of determinants for two periods separated by 20 years (1986–1987 and 2006–2007). To identify spatial groupings of coefficients, we perform a cluster analysis based on t-values of the geographically weighted regression.ResultsThe geographically weighted regression analysis shows that relationships between the under-five mortality rate and factors for socioeconomic, development, and environmental health factors vary spatially in terms of direction, strength, and extent when considering: female literacy and labor force participation; share of scheduled castes and scheduled tribes; access to electricity; safe water and sanitation; road infrastructure; and medical facilities. This spatial heterogeneity is accompanied by significant changes over time in the roles that these factors play in under-five mortality. Important local determinants of under-five mortality in 2011 were female literacy, female labor force participation, access to sanitation facilities and electricity; while the key local determinants in 1991 were road infrastructure, safe water, and medical facilities. We identify six different clusters based on geographically weighted regression coefficients that broadly encompass the same districts in both periods; but these clusters do not follow the regional boundaries suggested by the previous studies. In particular, the high mortality states of India that are often typically classified as high focus states were classified into three different clusters based on the relationship of the factors associated with under-five mortality.ConclusionThis study demonstrates the utility of combining geographically weighted regression and cluster analyses as a methodological approach to study local-level variation in public health indicators, and it could be applied in any country using aggregate-level information from census or survey data. Identifying local predictors of under-five mortality is important for designing interventions in specific districts. Additional reduction in under-five mortality will only be possible with intervention programs designed at the local level, which take into consideration local level determinants of under-five mortality.

Highlights

  • Reducing the under-five mortality rate (U5MR) by twothirds was a key Millennium Development Goal, and tracking progress in this goal has spurred a flurry of methodological developments in generating robust estimates of U5MR at the national scale [1,2,3]

  • According to the 1991 census, most 1986–1987 U5MR estimates for the districts in the south of the country varied between 50 and 100 under-5 deaths per 1000 live births, and a few districts had less than 50 under-5 deaths per 1000 live births in the south-west of the country

  • There were only modest changes in the geography of U5MR from 1986–1987 to 2006–2007, with a clear cluster of high U5MR districts remaining in the center of the country and low U5MR pockets persisting in the south

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Summary

Introduction

Reducing the under-five mortality rate (U5MR) by twothirds (between 1990 and 2015) was a key Millennium Development Goal, and tracking progress in this goal has spurred a flurry of methodological developments in generating robust estimates of U5MR at the national scale [1,2,3]. All countries should aim to reduce neonatal mortality to at least as low as 12 deaths per 1000 live births, and U5MR should be at least as low as 25 deaths per 1000 live births [4]. With this new SDG agenda, it is crucial to develop subnational estimates to ensure that no one is left behind, especially in large and decentralized countries such as India. India has the largest number of under-five deaths globally, and large variations in under-five mortality persist between states and districts. This study seeks to unravel local variation in key determinants of under-five mortality based on the 1991 and 2011 censuses

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