Abstract
Nuclear data are important for production and medical application of a radionuclide. This brief review concentrates on nuclear reaction cross-section data. The availability of standardized nuclear data for accelerator-based production of medical radionuclides is outlined. Some new directions in radionuclide applications, for example, theranostic approach, bimodal imaging, and radionuclide targeted therapy, are considered and the status of relevant nuclear data is discussed. The current trends in nuclear data research using accelerators are elaborated. The increasing significance of intermediate energy accelerators in production of therapeutic radionuclides is emphasized.
Highlights
Radionuclides find application in medicine, both in diagnosis and internal radiotherapy
Diagnostic investigations are carried out using short-lived radionuclides which emit either a single or major γ-ray of energy between 100 and 250 keV or a positron, the former in single photon emission computed tomography (SPECT) and latter in positron emission tomography (PET)
Nuclear data play an important role in the production and medical application of accelerator-based radionuclides
Summary
Radionuclides find application in medicine, both in diagnosis and internal radiotherapy. Radionuclidic purity reduces the radiation dose due to impurities and higher specific activity ensures that the biological equilibrium is not disturbed and imaging is carried out at real molecular level. Those two parameters are controlled by knowledge of nuclear reaction cross sections, especially in production of radionuclides via charged particle-induced reactions [1, 2]. Nuclear data play a continuing role in the development of radionuclides for applications In this brief review, the availability of standardized data for production of medical radionuclides using. Nuclear Data for Medical Radionuclides accelerators is outlined, some new directions in radionuclide applications are discussed, and the current trends in nuclear data research are described
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