Abstract

Background: Unraveling the relationship between health-related quality of life (HRQOL) instruments and the International Classification of Functioning, Disability, and Health (ICF) seems essential due to the increasing importance of quality of life evaluations in patients with heart failure (HF) and the use of the ICF for comparative purposes. The aim of this study is to identify and compare the content of HRQOL instruments for HF using the ICF coding system. Methods : In a 2-stage design, first we will identify all measures used to assess HRQOL for patients with HF and second we will compare the content of those measures using the ICF coding system. Systematic search will be performed in in MEDLINE, CINAHL, and Scopus databases using a combination of free texts and MeSH terms between January 1960 and January 2017. All instruments will be linked to the ICF separately by 2 reviewers according to 10 linking rules developed for this purpose. The degree of agreement between the reviewers will be calculated via the kappa statistic. Discussion: The results of this study may help clinicians and researchers to select the most appropriate outcome measure according to the ICF-based content validity.

Highlights

  • Based on the Framingham studies, the incidence of heart failure (HF) is increasing among older individuals, which is concerning given the aging of the population.[8]

  • Studies foretaste the increase of HF prevalence in the United States up to 46% by the year 2030.9 The spreading prevalence of HF might give forth increasing incidence, an aging population, improvements in the treatment of acute cardiovascular disease and HF, or a combination of these factors.[5]

  • It is possible to assess the heterogeneity of health-related quality of life (HRQOL) instruments in HF regarding the presentation of b, s, d, and e

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Summary

Introduction

Heart failure (HF) constitutes a major public health problem, with a current prevalence of 5.8 million in the USA and 26 million worldwide.[1, 2] The incidence of HF in the United States is 870 000 individuals newly diagnosed each year.[3, 4] Research in previous years showed that about 2.2% of the population in the United States suffered from HF.[2, 5] Since HF is an age-dependent syndrome, its prevalence increases from less than 1% in persons aged under 40 years to more than 10% in those aged over 80 years.[4, 6, 7] Based on the Framingham studies, the incidence of HF is increasing among older individuals, which is concerning given the aging of the population.[8]. Unraveling the relationship between health-related quality of life (HRQOL) instruments and the International Classification of Functioning, Disability, and Health (ICF) seems essential due to the increasing importance of quality of life evaluations in patients with heart failure (HF) and the use of the ICF for comparative purposes. The aim of this study is to identify and compare the content of HRQOL instruments for HF using the ICF coding system

Methods
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Conclusion

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