Abstract

In the context of a Klebsiella pneumoniae ESBL+ (KPE+) outbreak in a neonatal intensive care unit (NICU), hygiene practices and hospital environment were investigated. One hundred and seventy-one cases of colonized newborns, of whom 21 were confirmed as infected (clinical signs associated with positive C-reactive protein and/or positive blood culture), were recorded. The infection caused the death of 3 infants among the 21 infected ones. The outbreak was stopped by improving the basic hygiene measures such as the hands washing, the use of disposable gloves and gowns and by removing a potential environmental contamination source: the water bottle warmer.

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