Abstract
Purpose Heightened awareness of hazardous drug contamination in the workplace has increased the number of marketed, closed-system drug transfer devices (CSTDs). Currently, no official specifications for a closed-system device are available. Therefore, it is important to validate each system against the recommendations given by International Society of Oncology Pharmacy Practitioners and the National Institute for Occupational Safety and Health to make the best decision for an institution. Summary Titanium tetrachloride was selected to simulate the escape of vapor from each product. The second evaluation concentrated on the “dry connections” between the vial and syringe during drug preparation and between the syringe and access port during administration. Fluorescein sodium was selected to simulate contamination with the dry connections between the vial and syringe and between the syringe and access port. Conclusion The 2 studies found that only 1 of the 5 devices tested met the criteria or definition of a CSTD.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
