Contact sensitization to 6α-methylprednisolone aceponate

Abstract

Increasing attention has been focused on contact sensitization to topical corticosteroids in the past several years. In most cases, allergy to topical corticosteroids occurs in patients with long-lasting eczematous diseases. Cross-allergy between topical corticosteroid molecules is very common, and four groups of cross-reacting molecules have been recognized. In this report, we describe a girl with atopic dermatitis and sensitized to hydrocortisone-17-butyrate who became sensitized to 6α-methylprednisolone aceponate. Cross-sensitization between the two molecules is suggested.