Abstract
Seborrheic dermatitis (SD) is a common dermatological disorder, which affects about 2-3% of the population. The etiology of this disease is poorly understood. There is increasing acceptance of the proposition that Malassezia yeasts play some role in the development of SD. Seven of the nine known Malassezia yeast species are normal commensals of adult human skin. These species are Malassezia furfur, M. sympodialis, M. dermatis, M. restricta, M. slooffiae, M. obtusa, and M. globosa. The species that have been commonly associated with SD are M. globosa and M. restricta. However, other investigators have found M. furfur, M. sympodialis, M. obtusa and M. slooffiae as well. Abnormal or inflammatory immune system reactions to these yeasts may be related to development of this disease. Antifungal and anti-inflammatory preparations have been used to treat SD effectively and safely. The fact that antifungals are effective in the treatment and prophylaxis of SD further supports the role of Malassezia species in this disease.
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