Abstract
SUMMARY. The source, nature and properties of propolis (bee g̀lue) are described and the world literature on propolis dermatitis is reviewed. Propolis has been shown by a field survey to be a significant cause of occupational dermatitis in beekeepers in Britain, of which at least 0·05% are probably affected. Fourteen proven cases are recorded and 11 possible cases are mentioned. The clinical features are described and the possible effects of the volatile fraction of propolis are discussed. Prophylactic measures are suggested. Patch tests were carried out with propolis from different sources. Balsam of Peru, poplar and other tree resins, the volatile fraction of propolis and certain cinnamic derivatives. It is concluded that the allergens in propolis are derived mainly from poplar but also from other tree resins. None of the cinnamic derivatives so far tested appears to be the principal allergen involved.
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