Abstract
Animal data indicates that dietary cottonseed oil (CSO) may lower cholesterol; however, the effects of a CSO-rich diet have not been evaluated in humans. Thirty-eight healthy adults (aged 18%#x2013;40; 12 males, 26 females) consumed a CSO rich diet (95 g CSO daily) for one week. Anthropometric measurements were obtained, and blood was drawn pre- and post-intervention. Serum lipids (total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), and free fatty acids (FFA)) were assayed. There was no change in weight or waist circumference among participants. There was no change in HDL (Pre: 1.27 ± 0.4 mmol/L; Post: 1.21 ± 0.3 mmol/L) or TG (Pre: 0.91 ± 0.6 mmol/L; Post: 1.06 ± 1.0 mmol/L). Total cholesterol and LDL were reduced (TC Pre: 4.39 ± 0.9 mmol/L; Post: 4.16 ± 0.8 mmol/L; LDL Pre: 2.70 ± 0.8 mmol/L; Post: 2.47 ± 0.6 mmol/L). When data were grouped by sex, total cholesterol was reduced in female participants (Pre: 4.34 ± 0.9 mmol/L; Post: 4.09 ± 0.8 mmol/L). Consumption of a high fat, CSO-rich diet for one week reduced total cholesterol in female participants without reducing HDL.
Highlights
Hypercholesterolemia, increases in LDL-cholesterol, have been clearly associated with increased risk for cardiovascular disease [1,2]
Analysis of the baseline diet of participants based on the 24 h recall (Table 1) revealed lower baseline energy intake for males and females compared to the study diet
We conclude that Cottonseed oil (CSO) may lower cholesterol effectively, possibly making it a good candidate for inclusion in margarines and shortening, where it originated
Summary
Hypercholesterolemia, increases in LDL-cholesterol, have been clearly associated with increased risk for cardiovascular disease [1,2]. In strategies for prevention of hypercholesterolemia and Nutrients 2012, 4 subsequent management of cardiovascular disease, modification of body mass index (BMI), diet, and lifestyle have important roles to play [1]. Its consumption throughout the world has remained relatively steady over the past 5 years with approximately 4.8 million metric tons consumed in 2006/2007 and 4.6 in 2009/2010. This is higher than consumption of olive oil (2.9 million metric tons) [6]. Despite its common uses in food production, its role in lipid metabolism in humans remains largely unknown [7]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
